Abstract
Effect of hypermagnesemia on NMF was studied in 2 groups. Group A-hypermagnesemic (HM) infants of magnesium sulfate (MS) treated preeclamptic mothers. Cord blood Mg++(CBM) was 4.2±0.7 mg/dl. Group B-control infants of normal non MS treated mothers (CBM 1.5±0.2 mg/dl). Tension(t) generated by thenar muscle concentration in response to ulnar nerve stimulation was measured by recording initial train of 4 (T4=4 stimuli ½ sec. apart), tetany produced by 50 and 100 Hz stimuli, and post-tetanic T4. Results are expressed as %fade ([(tinitial-tfinal)/tinitial] × 100).
Neonatal hypermagnesemia results in significant (values underlined = p < 0.005) impairment of NMF during the first 24 hrs. of life.
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Rasch, D., Huber, P., Richardson, C. et al. 360 EFFECT OF HYPERMAGNESEMIA ON NEONATAL NEUROMUSCULAR FUNCTION (NMF). Pediatr Res 15 (Suppl 4), 500 (1981). https://doi.org/10.1203/00006450-198104001-00371
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DOI: https://doi.org/10.1203/00006450-198104001-00371