Abstract
Young children with ILD may be uncooperative or too ill to perform meaningful tests of pulmonary function. We have evaluated children with ILD using pre, during (DUR), and post exercise (EX) stress ear oximetry (SaO2) and other more routine tests of pulmonary function. Responses in children with ILD, healthy children (CON), those with bronchial asthma (BA), and cystic fibrosis (CF) were compared.
* all values represent averages ** standard error of the mean Exercise produced significant DeSaO2 (PRE-DUR) in the ILD, CF, and control groups. The control group DeSaO2 response was minimal. The ILD group exhibited the greatest changes. The alterations in the CF subjects were intermediate in degree. Desaturation responses during exercise clearly separated the ILD group from the others and correlated well with low FVC (R2=.60). Post EX SaO2 values promptly returned to near baseline in most children. We have found DeSaO2 during exercise to be a sensitive, and reproducible test of ILD in children.
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Beckerman, R., Mather, F., Bose, M. et al. 1626 PHYSIOLOGICAL CORRELATES OF INTERSTITIAL LUNG DISEASE (ILI)) IN CHILDREN: OXYGEN DESATURATION (DeSaO2) DURING EXERCISE. Pediatr Res 15 (Suppl 4), 714 (1981). https://doi.org/10.1203/00006450-198104001-01643
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DOI: https://doi.org/10.1203/00006450-198104001-01643