Abstract
BAER may be useful in localizing nonstructural defects in the brainstem. Two infants with CAHS were evaluated with tests of ventilation {VE awake(AW)/PaCO2, VE asleep(AS)/PaCO2}, routine neurological studies and BAER in order to assess the correlation between BAER and loss of central control of ventilation. BAER were also measured in normal infants (CON) and in an infant with prolonged sleep apnea (PSA) but without alveolar hypoventilation.
All BAER values in the CON subjects were normal. All three patients have exhibited depressed ventilatory response to CO2 during quiet sleep and prolongation of intrapeak latencies between waves I→III suggesting significant conduction delays in the lower brainstem. These studies suggest that BAER may be helpful in localizing defects in brainstem function implied by loss of metabolic control of ventilation during sleep.
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Beckerman, R., Meltzer, J., Dunn, P. et al. 1560 BRAINSTEM AUDITORY EVOKED RESPONSES (BAER) IN. INFANTS WITH CONGENITAL ALVEOLAR HYPOVENTILATION SYNDROME(CAHS). Pediatr Res 15 (Suppl 4), 703 (1981). https://doi.org/10.1203/00006450-198104001-01577
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DOI: https://doi.org/10.1203/00006450-198104001-01577