Abstract
A Puerto Rican girl with history of impetigo at 3 weeks of age was admitted with diagnosis of pneumonia at 5 months of age. Her WBC: 5800 with Poly: 1 Eo: 1 L: 79 M: 19%. The bone marrow was normal with increased number of myeloid cells, without maturation arrest. The subcutaneous epinephrine as well as intravenous hydrocortisone injections did not increase the total WBC's as well as percentage of PMNs. The PMN chemotaxis and random motility was grossly abnormal. For the next 10 months the WBC and % of PMN did not change, and she had a number of URI's and gingivitis, then she was lost to follow up. At 3 years of age when she was seen again with WBC:7150 Poly:45 Eo:1 L:48 M:6%. The epinephrine stimulation showed a 116% increase in absolute PMN count at 5′ and hydrocortisone injection increased the PMN count 4560 above the baseline at 3 hours. PMN chemotaxis was normal.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fikrig, S., Bhassin, Y., Phillips, J. et al. 910 TRANSIENT LAZY LEUKOCYTE SYNDROME. Pediatr Res 15 (Suppl 4), 594 (1981). https://doi.org/10.1203/00006450-198104001-00935
Issue Date:
DOI: https://doi.org/10.1203/00006450-198104001-00935