Abstract
We reviewed the clinical and laboratory features of 6 children with MCTD (4 girls, 2 boys). Initial symptoms (mean age of onset 9.2 years) were arthritis (2), chronic fevers (2), and urticaria and Raynaud's phenomenon (2). Mean age at diagnosis was 14.2 years. Clinical features included:
There has been no mortality, but 3/6 are significantly disabled (mean followup of 3.4 years) despite treatment with sallcylates, prednisone and in 3 patients chlorambucil. Our experience with MCTD in children reflects greater chronic morbidity than reported in adults.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chudwin, D., Wara, D., Cowan, M. et al. 905 CHILDHOOD MIXED CONNECTIVE TISSUE DISEASE. Pediatr Res 15 (Suppl 4), 593 (1981). https://doi.org/10.1203/00006450-198104001-00930
Issue Date:
DOI: https://doi.org/10.1203/00006450-198104001-00930