Abstract
Since April 1974, the Quebec Screening Network for Metabolic Diseases has been screening every infant born in the P.Q. for neonatal hypothyroidism. Since January 1977 every infant detected and treated is tested for its psychological and neuromuscular development at age 12, 18 and 36 months by the Griffith test. Over that period 20 infants age 12 months have been assessed. This assessment comprises 5 different test for locomotor development, social behavior, verbal, fine coordination and performance.
Nine of these infants have been retested at 18 months of age, with similar scores. These results appears to indicate that early treatment of congenital hypothyroidism if effective in preventing neuromuscular and mental retardation in 12 and 18 months infants as assessed by the Griffith test.
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Dussault, J., Glorieux, J., Letarte, J. et al. 293 PRELIMINARY REPORT ON PSYCHOLOGICAL DEVELOPMENT AT AGE ONE OF TREATED HYPOTHYROID INFANTS DETECTED BY THE QUEBEC SCREENING NETWORK FOR METABOLIC DISEASES. Pediatr Res 12 (Suppl 4), 412 (1978). https://doi.org/10.1203/00006450-197804001-00298
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DOI: https://doi.org/10.1203/00006450-197804001-00298