Abstract
Abnormal cardiac findings detected by echo in IDM have been emphasized but there is scant information of incidence, severity or pathogenesis. Thus, a prospective controlled study of 30 IDM and concurrent 36 normal newborns (N) was undertaken. There were no significant differences in mean ±S.E. birth wt. or gest. age of the IDM (3590±125g, 36.9±1.6 wk) compared to N (3383±899g, 39. 6±3.7wk). There were 17 Class A, 13 insulin dependent IDM. Respiratory distress (RDS) was seen in 9, hypoglycemia (H) in 9 and polycythemia (P) in 9 IDM. Echos (85) were done at 24-72 hr and/or 5-7 d. Findings at 24-72 hr. are listed:
Left vent. function, estimated from % shortening (ΔD) of LVD was depressed *p<.01 in IDM but were similar to N(26.8±1.3 vs 27. 9±1.4 respectively)at 5-7 d . No differences were seen between IDM and N in any of the other factors including LV-PEP or RV-PEP. Class of diabetes, RDS, H or P did not influence echo findings. Thus, echo abnormalities were limited to transient and mild depression of LV function as judged by % shortening.
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Lendrum, B., Pildes, R., Srinivasan, G. et al. 130 ECHOCARDIOGRAPHY (ECHO) STUDIES IN INFANTS OF DIABETIC MOTHERS (IDM). Pediatr Res 12 (Suppl 4), 385 (1978). https://doi.org/10.1203/00006450-197804001-00135
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DOI: https://doi.org/10.1203/00006450-197804001-00135