Abstract
Cord blood cholesterol (C), triglyceride (TG), high density C (C-HDL), low density C(C-LDL) and C-HDL/C-LDL were quantitated in 117 neonates (58 white, 59 black) to assess for neonatal expression of racial lipid differences. The 117 neonates were studied in their consecutive birth order in a lipoprotein survey of 3000 births. Comparisons of cord blood lipoproteins were made using the following groups: all black(B) vs all white(W), all male(M) vs all female(F), and sex-race interaction. Tests of difference were made using the general linear hypothesis method, allowing analyses of variance on data composed of unequal numbers of observations:
There were no black-white or male-female differences in cord blood C, C-HDL, C-LDL, or C-HDL/C-LDL. Cord blood TG was slightly higher in black neonates, p<.02. For all 117 neonates, C-HDL correlated with total C (r=.63, p<.001), but not with C-LDL (r=.002). At comparable total C levels there were no neonatal black-white differences in C-HDL in contrast to older children and adults, where blacks have higher mean C-HDL. Within the limitations of “genicity” as expressed by cord blood lipoproteins, black-white C-HDL differences are not apparent at birth and may be acquired later in childhood.
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Glueck, C., Gartside, P., Tsang, R. et al. BLACK-WHITE SIMILARITIES IN CORD BLOOD LIPIDS AND LIPOPROTEINS. Pediatr Res 11, 435 (1977). https://doi.org/10.1203/00006450-197704000-00396
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DOI: https://doi.org/10.1203/00006450-197704000-00396