Abstract
Immediate postmortem injection of radiopaque modified Schlesinger mass into the pulmonary arteries of infants dying of hyaline membrane disease and a control group dying of other causes revealed marked discrepancies between the degrees of small vessel filling. The lungs in hyaline membrane disease revealed the typical muscular arterial tortuosity and pruned tree appearance of pulmonary hypertension as manifest on in vivo pulmonary angiography. The lungs of the control group revealed perfusion of all arterial and arteriolar branches as seen in normal pulmonary arteriograms suggesting that pulmonary hypo-perfusion plays a role in the causation or may be the result of hyaline membrane disease. These findings support previous clinical demonstrations of pulmonary hypertension and pulmonary hypo-perfusion in this disease.
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O'Connor, J., Ingall, D., Castro, S. et al. POST MORTEM PULMONARY ARTERIAL INJECTION STUDIES IN HYALINE MEMBRANE DISEASE. Pediatr Res 8, 448 (1974). https://doi.org/10.1203/00006450-197404000-00651
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DOI: https://doi.org/10.1203/00006450-197404000-00651