Abstract
RICHARD W.NEWCOMB (Children's Asthma Research Institute, Denver, Colo.): Do you have any idea how the antibody titers in your nasal fluids relate to immunoglobulin concentrations?
Dr. OGRA: We are working on it at the moment. It seems that total gamma-A-immunoglobulin concentration decreases by about twofold, but it is not as constant as the drop in the specific viral antibody.
E.RICHARD STIEHM (UCLA Center for the Health Sciences): What is the relative contribution of the tonsillectomy and the adenoidectomy to the immune deficiency noted?
Dr. OGRA: It is very hard these days to pick up children who have had isolated tonsillectomies. I do not have any information on the individual participation of tonsils and adenoids. Most of the children we studied had complete removal of tonsils as well as adenoids.
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Ogra, P., Karzon, D. Role of Nasopharyngeal Tonsils in the Mechanism of Mucosal Immunity to Poliovirus.. Pediatr Res 4, 510 (1970). https://doi.org/10.1203/00006450-197011000-00003
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DOI: https://doi.org/10.1203/00006450-197011000-00003