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Biopolymers, Bio-related Polymer Materials

Metal nanoarchitecture fabrication using DNA as a biotemplate

Polymer Journal volume 49, pages 815824 (2017) | Download Citation

Abstract

Among the many important biopolymers, DNA has been a key component in material sciences and nanotechnology. We have focused on the fabrication of metal nanoarchitectures using DNA as a template due to its intrinsic properties and advantages, such as a well-ordered structure, rich chemical functionality and programmable base-pairing interactions, as well as the availability of multiple enzymes for DNA manipulation. In this review, various methods for the fabrication of DNA-templated metal nanoarchitecture are introduced. The methods include DNA-mediated metal nanoparticle formation, DNA-templated conductive nanowire fabrication by metal depositions, sequence-selective metal deposition onto DNA for elaborate nanowire fabrication and DNA brushes as templates for use on solid substrates. DNA sequence-selective binding of metal ions and metal complexes and subsequent reduction to metals are fundamental issues for the fabrication of metal nanoarchitectures. The resultant metal nanoparticles and their assemblies can be used as functional nanomaterials in applications such as catalysts, conducting nanowires, optical nanomaterials and especially in metamaterials. This biopolymer-templating method can be applied not only to metal deposition but also to the assembly of functional molecules.

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References

  1. 1.

    & Localized surface plasmon resonance spectroscopy and sensing. Annu. Rev. Phys. Chem. 58, 267–297 (2007).

  2. 2.

    , , , , , & Nanostructured plasmonic sensors. Chem. Rev. 108, 494–521 (2008).

  3. 3.

    , , , , , & Plasmon–molecule interactions. Nano Today 5, 494–505 (2010).

  4. 4.

    , , , , , & Active gap SERS for the sensitive detection of biomacromolecules with plasmonic nanostructures on hydrogels. Adv. Opt. Mater. 4, 259–263 (2016).

  5. 5.

    & Nanoelectronics from the bottom up. Nat. Mater. 6, 841–850 (2007).

  6. 6.

    , , , , , , & Metallization of branched DNA origami for nanoelectronic circuit fabrication. ACS Nano 5, 2240–2247 (2011).

  7. 7.

    , , , , , , , & Metallized DNA nanolithography for encoding and transferring spatial information for graphene patterning. Nat. Commun. 4, 1663 (2013).

  8. 8.

    , & Molecular imprinting science and technology: a survey of the literature for the years 2004-2011. J. Mol. Recognit. 27, 297–401 (2014).

  9. 9.

    , , , , , , & Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003. J. Mol. Recognit. 19, 106–180 (2006).

  10. 10.

    & DNA-templated organic synthesis: Nature’s strategy for controlling chemical reactivity applied to synthetic molecules. Angew. Chem. Int. Ed. 43, 4848–4870 (2004).

  11. 11.

    , , & A DNA-based method for rationally assembling nanoparticles into macroscopic materials. Nature 382, 607–609 (1996).

  12. 12.

    , , , , , & Organization of ‘nanocrystal molecules’ using DNA. Nature 382, 609–611 (1996).

  13. 13.

    Folding DNA to create nanoscale shapes and patterns. Nature 440, 297–302 (2006).

  14. 14.

    , , , , & DNA-templated self-assembly of metallic nanocomponent arrays on a surface. Nano Lett. 4, 2343–2347 (2004).

  15. 15.

    , , , & DNA-templated self-assembly of two-dimensional and periodical gold nanoparticle arrays. Angew. Chem. Int. Ed. 45, 730–735 (2006).

  16. 16.

    , , , , , , , , & Encapsulation of a gold nanoparticle in a DNA origami container. Polym. J. 47, 177–182 (2014).

  17. 17.

    , & Wireframe and tensegrity DNA nanostructures. Acc. Chem. Res. 47, 1691–1699 (2014).

  18. 18.

    , , & Structural DNA nanotechnology : state of the art and future perspective. J. Am. Chem. Soc. 136, 11198–11211 (2014).

  19. 19.

    & DNA origami: the art of folding DNA. Angew. Chem. Int. Ed. 51, 58–66 (2012).

  20. 20.

    & Nanomechanical molecular devices made of DNA origami. Acc. Chem. Res. 47, 1742–1749 (2014).

  21. 21.

    & DNA nanostructures as scaffolds for metal nanoparticles. Polym. J. 44, 452–460 (2012).

  22. 22.

    , & Sites and thermodynamic quantities associated with proton and metal ion interaction with ribonucleic acid, deoxyribonucleic acid, and their constituent bases, nucleosides, and and nucleotides. Chem. Rev. 71, 439–482 (1971).

  23. 23.

    , , & DNA-templated Ag nanocluster formation. J. Am. Chem. Soc. 126, 5207–5212 (2004).

  24. 24.

    , , , , & Ag nanocluster formation using a cytosine oligonucleotide template. J. Phys. Chem. C 111, 175–181 (2007).

  25. 25.

    , , , , , , & Oligonucleotide-stabilized Ag nanocluster fluorophores. J. Am. Chem. Soc. 130, 5038–5039 (2008).

  26. 26.

    , , , & Sequence-dependent fluorescence of DNA-hosted silver nanoclusters. Adv. Mater. 20, 279–283 (2008).

  27. 27.

    , , , , & Chirality of silver nanoparticles synthesized on DNA. J. Am. Chem. Soc. 128, 11006–11007 (2006).

  28. 28.

    Deoxyribozymes: DNA catalysts for bioorganic chemistry. Org. Biomol. Chem. 2, 2701–2706 (2004).

  29. 29.

    , & DNA-templated photoinduced silver deposition. J. Am. Chem. Soc. 127, 11216–11217 (2005).

  30. 30.

    , , , , , , , & Inspiration from chemical photography: accelerated photoconversion of AgCl to functional silver nanoparticles mediated by DNA. Chem. Commun. 47, 9426–9428 (2011).

  31. 31.

    , , , , & DNA-templated plasmonic Ag/AgCl nanostructures for molecular selective photocatalysis and photocatalytic inactivation of cancer cells. J. Mater. Chem. B 1, 5899 (2013).

  32. 32.

    , , , , & DNA-modulated photo-transformation of AgCl to silver nanoparticles: visiting the formation mechanism. J. Colloid Interface Sci. 452, 224–234 (2015).

  33. 33.

    & DNA electronics. Physica E Low Dimens. Syst. Nanostruct. 33, 1–12 (2006).

  34. 34.

    & DNA-templated fabrication of 1D parallel and 2D crossed metallic nanowire arrays. Nano Lett. 3, 1545–1548 (2003).

  35. 35.

    , , & Platinated DNA as precursors to templated chains of metal nanoparticles. Adv. Mater. 13, 1793–1797 (2001).

  36. 36.

    , & Fabrication of silver nanowires by selective electroless plating of DNA stretched using the LB method. Chem. Lett. 34, 112–113 (2005).

  37. 37.

    , , , , , , & Conductive metal nanowires templated by the nucleoprotein filaments, complex of DNA and RecA protein. J. Am. Chem. Soc. 127, 8120–8125 (2005).

  38. 38.

    , , & Polyaniline nanowires on Si surfaces fabricated with DNA templates. J. Am. Chem. Soc. 126, 7097–7101 (2004).

  39. 39.

    , , , , & DNA-templated semiconductor nanoparticle chains and wires. Adv. Mater. 19, 1748–1751 (2007).

  40. 40.

    , , , , , & Synthesis, manipulation and conductivity of supramolecular polymer nanowires. Chem. A Eur. J. 13, 822–828 (2007).

  41. 41.

    , , , , , , & Templating Ag on DNA/polymer hybrid nanowires: control of the metal growth morphology using functional monomers. Electrochem. Commun. 11, 550–553 (2009).

  42. 42.

    , , , , , & Directed DNA metallization. J. Am. Chem. Soc. 128, 1398–1399 (2006).

  43. 43.

    , , & DNA-templated assembly and electrode attachment of a conducting silver wire. Nature 391, 775–778 (1998).

  44. 44.

    , & Fabrication of metal nanowires by electroless plating of DNA. e-J. Surf. Sci. Nanotechnol. 3, 82–85 (2005).

  45. 45.

    , , & DNA-based routes to semiconducting nanomaterials. Chem. Commun. 1797–1806 (2009).

  46. 46.

    , , , & DNA-templated nanowires: morphology and electrical conductivity. Nanoscale 6, 4027–4037 (2014).

  47. 47.

    , , , , , , , & Novel charge transport in DNA-templated nanowires. J. Mater. Chem. 22, 13691–13697 (2012).

  48. 48.

    , , , , , & Fabrication of nanoscale gaps using a combination of self-assembled molecular and electron beam lithographic techniques. Appl. Phys. Lett. 88, 1–4 (2006).

  49. 49.

    & Coulomb blockade and hopping conduction in PbSe quantum dots. Phys. Rev. Lett. 95, 1–4 (2005).

  50. 50.

    , & Room-temperature Coulomb blockade effect in silicon quantum dots in silicon nitride films. Appl. Phys. Lett. 89, 13116 (2006).

  51. 51.

    , , , , , , & One by one single-electron transport in nanomechanical Coulomb blockade shuttle. Appl. Phys. Lett. 91, 1–4 (2007).

  52. 52.

    , , , , , & DNA origami metallized site specifically to form electrically conductive nanowires. J. Phys. Chem. B 116, 10551–10560 (2012).

  53. 53.

    , , , , , , & DNA origami-templated growth of arbitrarily shaped metal nanoparticles. Small 7, 1795–1799 (2011).

  54. 54.

    , , , , & Rapid metallization of lambda DNA and DNA origami using a Pd seeding method. J. Mater. Chem. 21, 12126 (2011).

  55. 55.

    , , , , & Sequence-specific molecular lithography on single DNA molecules. Science 297, 72–75 (2002).

  56. 56.

    , , , & DNA-templated carbon nanotube field-effect transistor. Science 302, 1380–1382 (2003).

  57. 57.

    , & Nanoscale programmable sequence-specific patterning of DNA scaffolds using RecA protein. Nanotechnology 23, 365301 (2012).

  58. 58.

    , , , & In vitro synthesis of uniform poly (dG)– poly (dC) by Klenow exo À fragment of polymerase I. Nucleic Acid Res. 33, 525–535 (2005).

  59. 59.

    , & Fold-back structures at the distal end influence DNA slippage at the proximal end during mononucleotide repeat expansions. Nucleic Acids Res. 27, 3851–3858 (1999).

  60. 60.

    & Slippage synthesis of simple sequence DNA. Nucleic Acids Res. 20, 211–215 (1992).

  61. 61.

    , , , , & In vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion. Nucleic Acids Res. 24, 2835–2840 (1996).

  62. 62.

    , , & Sequence-specifically platinum metal deposition on enzymatically synthesized DNA block copolymer. Chem. Commun. 4270–4272 (2008).

  63. 63.

    , & Human telomerase inhibition by 7-deaza-2‘-deoxypurine nucleoside triphosphates †. Biochemistry 35, 15611–15617 (1996).

  64. 64.

    , , & Direct voltammetric analysis of DNA modified with enzymatically incorporated 7-deazapurines. Anal. Chem. 82, 6807–6813 (2010).

  65. 65.

    , & Toward electrochemical resolution of two genes on one electrode: Using 7-deaza analogues of guanine and adenine to prepare PCR products with differential redox activity. Anal. Chem. 74, 347–354 (2002).

  66. 66.

    , , , , & Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin. Nature 377, 649–652 (1995).

  67. 67.

    , , , & Solution structure of a cisplatin-induced DNA interstrand cross-link. Science 270, 1842–1845 (1995).

  68. 68.

    , , & Study of the interaction of DNA with cisplatin and other Pd(II) and Pt(II) complexes by atomic force microscopy. Nucleic Acids Res. 26, 1473–1480 (1998).

  69. 69.

    , , , & Enzymatic synthesis of a DNA triblock copolymer that is composed of natural and unnatural nucleotides. Chem. Asian J. 10, 455–460 (2015).

  70. 70.

    , , , , , , , & Synthesis and properties of novel silver-containing DNA molecules. Adv. Mater. 28, 4839–4844 (2016).

  71. 71.

    , , , , , & Stepwise evolution of DNA-programmable nanoparticle superlattices. Angew. Chem. Int. Ed. 52, 6624–6628 (2013).

  72. 72.

    , & DNA microarrays : a powerful genomic tool for biomedical and clinical research. Mol. Med. 13, 527–541 (2007).

  73. 73.

    Applications of DNA microarrays in biology. Annu. Rev. Biochem. 74, 53–82 (2005).

  74. 74.

    , , , , & Surface-initiated controlled radical polymerization: state-of-the-art, opportunities, and challenges in surface and interface engineering with polymer brushes. Chem. Rev. 117, 1105–1318 (2017).

  75. 75.

    , , & Surface-initiated polymer brushes in the biomedical field: Applications in membrane science, biosensing, cell culture, regenerative medicine and antibacterial coatings. Chem. Rev. 114, 10976–11026 (2014).

  76. 76.

    Polymer brushes here, there, and everywhere: recent advances in their practical applications and emerging opportunities in multiple research fields. J. Polym. Sci. A Polym. Chem. 50, 3225–3258 (2012).

  77. 77.

    Polymer brushes: applications in biomaterials and nanotechnology. Polym. Chem. 1, 769 (2010).

  78. 78.

    , & A structural definition of polymer brushes. J. Polym. Sci. A Polym. Chem. 45, 3505–3512 (2007).

  79. 79.

    , , , , , & Wettability and antifouling behavior on the surfaces of superhydrophilic polymer brushes. Langmuir 28, 7212–7222 (2012).

  80. 80.

    Polymer-brush lubrication: a review of recent theoretical advances. Soft Matter 12, 3479–3501 (2016).

  81. 81.

    , , , & Fabrication of arbitrary three-dimensional polymer structures by rational control of the spacing between nanobrushes. Angew. Chem. Int. Ed. 50, 6506–6510 (2011).

  82. 82.

    , , & 3D-patterned polymer brush surfaces. Nanoscale 3, 4929 (2011).

  83. 83.

    , , & Collective conformations of DNA polymers assembled on surface density gradients. J. Am. Chem. Soc. 134, 3954–3956 (2012).

  84. 84.

    , , , & Entropy-driven collective interactions in DNA brushes on a biochip. Proc. Natl Acad. Sci. USA 110, 4534–4538 (2013).

  85. 85.

    , , , , , , , , & DNA brush-directed vertical alignment of extensive gold nanorod array with controlled density. ACS Omega 2, 2208–2213 (2017).

  86. 86.

    , , , & Device-scale perpendicular alignment of colloidal nanorods. Nano Lett. 10, 195–201 (2010).

  87. 87.

    , , , , , & Controlled semiconductor nanorod assembly from solution: influence of concentration, charge and solvent nature. J. Mater. Chem. 22, 1562–1569 (2012).

  88. 88.

    , , , , & Self-assembly of vertically aligned gold nanorod arrays on patterned substrates. Angew. Chem. Int. Ed. 51, 8732–8735 (2012).

  89. 89.

    , , , , , , & Nanoscale topographical control of capillary assembly of nanoparticles. Nat. Nanotechnol. 12, 73–80 (2017).

  90. 90.

    , , , , , , & Interfacial liquid-state surface-enhanced Raman spectroscopy. Nat. Commun. 4, 2182 (2013).

  91. 91.

    , , & Enzymatic fabrication of DNA nanostructures : extension of a self-assembled oligonucleotide monolayer on gold arrays. J. Am. Chem. Soc. 5, 14122–14123 (2005).

  92. 92.

    & Surface-initiated enzymatic polymerization of DNA. Langmuir 23, 11712–11717 (2007).

  93. 93.

    , & Fabrication of DNA polymer brush arrays by destructive micropatterning and rolling-circle amplification. Macromol. Biosci. 11, 607–617 (2011).

  94. 94.

    , , & Surface-initiated growth of poly d(A-T) by Taq DNA polymerase. Langmuir 21, 4669–4673 (2005).

  95. 95.

    , , , , & Preparation and characterization of double-stranded DNA brushes via surface-initiated enzymatic polymerization. J. Nanosci. Nanotechnol. in press

  96. 96.

    , , , , , & Fabrication of a novel cell culture system using DNA-grafted substrates and DNase. J. Biomed. Nanotechnol. 12, 286–295 (2016).

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Acknowledgements

This work was supported in part by the ‘Dynamic Alliance for Open Innovation Bridging Human, Environment and Materials’ from the Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT). This work was performed under the Cooperative Research Program of the ‘Network Joint Research Center for Materials and Devices’. A part of this work was conducted at Hokkaido University, supported by the ‘Nanotechnology Platform’ Program of the MEXT, Japan. Support from the Noguchi Institute (HM) is also acknowledged.

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Affiliations

  1. Research Institute for Electronic Science, Hokkaido University, Sapporo, Japan

    • Kuniharu Ijiro
    •  & Hideyuki Mitomo
  2. Global Station for Soft Matter, Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, Japan

    • Kuniharu Ijiro
    •  & Hideyuki Mitomo

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The authors declare no conflict of interest.

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Correspondence to Kuniharu Ijiro.

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https://doi.org/10.1038/pj.2017.63