Abstract
The enzymatic degradation of the chain-extended copoly[succinic anhydride (SA)/ethylene oxide (EO)], synthesized by the ring-opening copolymerization, was studied using the lipase from Rhizopus arrhizus. A decrease in SA content of these copolymers resulted in substantial increase of their degradability. The lipase concentration was shown to enhance considerably the degradation of the copolymer film (polymer composition SA/EO=42/58 mol%) which exhibited the highest susceptibility to degradation. The water contact angle measurements conducted on the films and their water absorption were related to the easy of adsorption of the lipase to the surface of the copolymer film and were not found to be particularly influenced by SA content. The degrees of crystallinity of the copolymer films, determined from wide angle X-ray diffraction, were within a range 24 to 28% as SA content increased from 42 to 48 mol%. The small angle X-ray scattering profiles indicated that these copolymer films had alternating crystalline layer structure. The long-period between lamellar crystalline, calculated from scattering angle, was found to increase from 80 to 110 Å with a decrease in SA content. The long-period, related to the size of amorphous region, was shown to affect the enzymatic degradation of copolymer by the lipase.
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Maeda, Y., Nakayama, A., Kawasaki, N. et al. The Morphology and Enzymatic Degradation of Chain-Extended Copoly(succinic anhydride/ethylene oxide) Films. Polym J 29, 836–842 (1997). https://doi.org/10.1295/polymj.29.836
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DOI: https://doi.org/10.1295/polymj.29.836