Abstract
Nucleic acid base derivatives were immobilized on 3-aminopropylsilanized silica (APS-silica) and silica gel. The bases immobilized were thymine, uracil, cytosine, adenine, guanine, and hypoxanthine. These silica gels were proved to be useful as columns of high performance liquid chromatography (HPLC) for the selective separation of nucleosides using specific interaction between complementary bases.
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Nagae, S., Miyamoto, T., Inaki, Y. et al. Functional Monomers and Polymers CLXXIII. Immobilization of Nucleic Acid Bases on Silica Gel and Application to HPLC for Selective Separation of Nucleosides. Polym J 21, 19–33 (1989). https://doi.org/10.1295/polymj.21.19
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DOI: https://doi.org/10.1295/polymj.21.19