Abstract
Nucleic acid analogs were prepared by grafting cytosine and hypoxanthine derivatives containing hydroxyl groups onto linear polyethyleneimine. The polymers contained about 90 unit mol% of the nucleic acid bases, and were easily soluble in water at neutral pH value. They were found to form polymer complexes with polynucleotides (PolyI and PolyC) by specific base-base interactions in aqueous solution.
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Wada, T., Inaki, Y. & Takemoto, K. Functional Monomers and Polymers CLXXI. Synthesis and Interaction Studies on Water Soluble Nucleic Acid Analogs: Polyethyleneimine Derivatives Containing Cytosine and Hypoxanthine. Polym J 21, 11–18 (1989). https://doi.org/10.1295/polymj.21.11
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DOI: https://doi.org/10.1295/polymj.21.11
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