Table 3 ROAST differential expression statistics (P-values shown) across the Cancer Genome Atlas ovarian-cancer gene-expression data set for gene sets defined by different histone marks

From: Chromatin H3K27me3/H3K4me3 histone marks define gene sets in high-grade serous ovarian cancer that distinguish malignant, tumour-sustaining and chemo-resistant ovarian tumour cells

Histone mark Tumour overexpressed, P-values Tumour downregulated, P-values
Bivalent 1 0.0022
H3K27me3 1 0.0031
H3K4me3 0.0055 1