Figure 1 | Nutrition & Diabetes

Figure 1

From: The cannabinoid Δ9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity

Figure 1

Effect of THCV on body weight gain, cumulative food intake and energy expenditure in DIO mice (study 1). (a) Body weight gain in the dose–response study, n=9 mice per treatment. (b) Cumulative food intake in mice given AM251 or THCV (12.5 mg kg−1 p.o.), n=3 groups of three mice per treatment (other dose levels of THCV excluded from graph for sake of clarity since identical to controls). However, all treatments were included in the one-way ANOVA statistical analysis. (c) Twenty-four-hour energy expenditure after 9 days treatment in DIO mice given AM251, (d) THCV (5 mg kg−1) or (e) THCV (12.5 mg kg−1 p.o.) in study 1, n=3 groups of three mice per treatment. ****P<0.0001 as compared to vehicle treated animals.

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