Table 3: Long-term changes in plasma values in non-diabetic and diabetic patients following BPD-DS surgery

From: Acylation stimulating protein reduction precedes insulin sensitization after BPD-DS bariatric surgery in severely obese women

VariablesNon-diabetic women n=32Diabetic women n=22
 Pre-operative6 months12 monthsP-valuePre-operative6 months12 monthsP-value
BMI (kg m−2)48.6±7.435.8±6.2*29.5±6.2*<0.00149.8±837.2±6.6*32±5.6*<0.001
Fat mass (kg)66.9±13.540.5±11.3*28.1±11.1*<0.00166.2±14.939.6±11.1*29.9±9.7*<0.001
Lean mass (kg)59.3±852.4±7.2*50.3±6*<0.00161±9.555.1±9.3*50.9±9.2*<0.001
Fat percentage (%)52.8±2.643±5.3*34.8±7.4*<0.00151.7±3.641.4±5.9*36.5±7.1*<0.001
         
TG (mmol l−1)1.38±0.571.17±0.35*0.98±0.4*<0.0011.81±0.821.6±0.811.34±0.34*<0.05
Apo-B (mmol l−1)0.79±0.160.57±0.1*0.48±0.09*<0.0010.75±0.20.67±0.310.61±0.17NS
NEFA (mmol l−1)0.55±0.120.51±0.170.52±0.17NS0.53±0.170.64±0.240.58±0.24NS
Chol (mmol l−1)4.8±0.683.26±0.59*3.24±0.55*<0.0014.53±1.043.58±0.97*3.66±0.72*<0.001
HDL-Chol (mmol l−1)1.4±0.31.06±0.28*1.26±0.29*<0.0011.26±0.350.98±0.29*1.09±0.25*<0.001
LDL-Chol (mmol l−1)2.78±0.591.66±0.4*1.54±0.37*<0.0012.45±0.771.87±0.81*1.96±0.65*<0.001
Fructosamine (umol l−1)202±5.0189±3.6197±2.5NS230±9.9203±5.1201±4.0NS
hsCRP (g l−1)10.1±1.54.0±0.91.6±0.3NS10.8±1.76.4±1.62.5±0.5NS
  1. Abbreviations; BMI, body mass index; Chol, cholesterol; hsCRP, high sensitivity C-reactive protein; NEFA, non-esterified fatty acid; TG, triglyceride. The values are presented as mean±s.d. and significant differences were analyzed by repeated measures ANOVA followed by Holm–Sidak post-hoc test (*P<0.05) vs preoperative state.