Figure 1

From: Dietary lipid-dependent regulation of de novo lipogenesis and lipid partitioning by ketogenic essential amino acids in mice

Figure 1

Effects of high-KAA diets on diet-induced obesity. Growth curves (a), body weights (b), average food intake (c), oxygen consumption (d), and respiratory quotient (e) of C57B6 mice fed for 4 weeks with or without KAA fortification under LFD and HFD conditions (mean±s.e.m., n=9 for each group). KAA fortifications were started after 2 months of pretreatment of LFD or HFD (shown as pre-LFD or pre-HFD). At day 0, the average body weights of mice under pre-LFD and pre-HFD conditions were 31.6±0.3 and 37.1±0.5, respectively. For oxygen consumption and respiratory quotients, values were obtained over 3 days following a week of acclimatization to the metabolic chamber, and only the results from the HFD with or without KAA fortification are shown. *P<0.05 for all high-KAA groups as compared with the control LFD or HFD groups. NS, not significant.