News & Views | Published:

At the end, remodeling leads to eviction

Nature Structural & Molecular Biology volume 12, pages 10281029 (2005) | Download Citation

Subjects

The induction and repair of chromosome breaks is associated with myriad changes in chromatin. A recent study shows that chromatin remodeling that results in histone eviction at the break site requires the Mre11 complex and INO80 and that these events are important for efficient loading of the Rad51 recombinase.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , , & Nature 438, 479–483 (2005).

  2. 2.

    et al. Curr. Opin. Genet. Dev. 12, 162–169 (2002).

  3. 3.

    et al. Nat. Cell Biol. 5, 675–679 (2003).

  4. 4.

    et al. Curr. Biol. 10, 886–895 (2000).

  5. 5.

    , , & J. Cell Biol. 146, 905–915 (1999).

  6. 6.

    et al. Curr. Biol. 14, 1703–1711 (2004).

  7. 7.

    et al. Nature 432, 406–411 (2004).

  8. 8.

    , , & Nature 406, 541–544 (2000).

  9. 9.

    et al. Nature 419, 411–415 (2002).

  10. 10.

    et al. Mol. Cell 16, 979–990 (2004).

  11. 11.

    et al. Cell 119, 767–775 (2004).

  12. 12.

    et al. Cell 94, 399–409 (1998).

  13. 13.

    et al. FEBS Lett. 579, 899–903 (2005).

  14. 14.

    , , & DNA Repair (Amst.) 3, 845–854 (2004).

  15. 15.

    , & Mol. Cell 7, 1255–1266 (2001).

  16. 16.

    & Genes Dev. 15, 2238–2249 (2001).

  17. 17.

    , & Nat. Cell Biol. 3, 844–847 (2001).

  18. 18.

    , , & Nat. Struct. Mol. Biol. 12, 403–407 (2005).

  19. 19.

    & Annu. Rev. Genet. 38, 233–271 (2004).

Download references

Author information

Affiliations

  1. The author is in Sloan Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. petrinij@mskcc.org

    • John H J Petrini

Authors

  1. Search for John H J Petrini in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nsmb1205-1028

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing