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Knowing when to let go

Nature Structural & Molecular Biology volume 12, pages 1026–1027 (2005)Cite this article

A new study sheds light on the mechanism regulating the translation of localized mRNAs at their destination. Phosphorylation of an RNA-binding protein by Src promotes complex disassembly and allows translation of the localized transcript.

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Figure 1: Model for ZBP1-dependent β-actin mRNA localization and translational control.

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Acknowledgements

We thank L. DesGroseillers and W. Sossin for sharing unpublished data and E. Querido for critical reading of the manuscript.

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  1. Département de Biochimie, Université de Montréal, Montréal, H3C 3J7, Québec, Canada

    Nicolas Paquin & Pascal Chartrand

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  1. Nicolas Paquin
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  2. Pascal Chartrand
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Paquin, N., Chartrand, P. Knowing when to let go. Nat Struct Mol Biol 12, 1026–1027 (2005). https://doi.org/10.1038/nsmb1205-1026

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