The recent crystal structure of tetra nucleosomes supports zigzag-based models of chromatin fiber structure. The next challenge is to understand the modulation of chromatin structure in the nucleus, characterized by variability in DNA, histones and non-histone components.
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Rachel A. Horowitz-Scherer
References
Schalch, T., Duda, S., Sargent, D.F. & Richmond, T.J. Nature 436, 138–141 (2005).
Gall, J. Science 139, 120–121 (1963).
Woodcock, C.L. & Dimitrov, S. Curr. Opin. Genet. Dev. 11, 130–135 (2001).
Dorigo, B. et al. Science 306, 1571–1573 (2004).
Lowary, P.T. & Widom, J. J. Mol. Biol. 276, 19–42 (1998).
Williams, S.P. et al. Biophys. J. 49, 233–248 (1986).
Woodcock, C.L., Frado, L.-L.Y. & Rattner, J.B. J. Cell Biol. 99, 42–52 (1984).
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Woodcock, C. A milestone in the odyssey of higher-order chromatin structure. Nat Struct Mol Biol 12, 639–640 (2005). https://doi.org/10.1038/nsmb0805-639
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DOI: https://doi.org/10.1038/nsmb0805-639
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