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Coil-in-to snRNP assembly and Cajal bodies

Eukaryotic cells have numerous non–membrane bound bodies whose functions are often unclear. On page 403 of this issue, Strzelecka and colleagues provide evidence that the ability to form Cajal bodies increases the rate of small nuclear ribonucleoprotein (snRNP) biogenesis and/or function. This supports the hypothesis that some cellular bodies form to increase the rates of assembly of multicomponent cellular machines.

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Figure 1: Interpretation of coilin effects on snRNP biogenesis and function.


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Correspondence to Roy Parker.

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Yoon, JH., Parker, R. Coil-in-to snRNP assembly and Cajal bodies. Nat Struct Mol Biol 17, 391–393 (2010).

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