An international conference focusing on the Hsp90 molecular chaperone was recently held in Seeon, Germany. The program provided a current synopsis on a wide array of topics, including structural insights, roles in established and novel cellular pathways and disease implications.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Whitesell, L. & Lindquist, S.L. Nat. Rev. Cancer 5, 761–772 (2005).
Ali, M.M. et al. Nature 440, 1013–1017 (2006).
Shiau, A.K., Harris, S.F., Southworth, D.R. & Agard, D.A. Cell 127, 329–340 (2006).
Riggs, D.L. et al. Crit. Rev. Biochem. Mol. Biol. 39, 279–295 (2004).
Wegele, H., Muller, L. & Buchner, J. Rev. Physiol. Biochem. Pharmacol. 151, 1–44 (2004).
Dittmar, K.D., Demady, D.R., Stancato, L.F., Krishna, P. & Pratt, W.B. J. Biol. Chem. 272, 21213–21220 (1997).
Grad, I. et al. Mol. Cell. Biol. 26, 8976–8983 (2006).
Vaughan, C.K. et al. Mol. Cell 23, 697–707 (2006).
Wang, X. et al. Cell 127, 803–815 (2006).
Wandinger, S.K., Suhre, M.H., Wegele, H. & Buchner, J. EMBO J. 25, 367–376 (2006).
Sanchez, E.R., Toft, D.O., Schlesinger, M.J. & Pratt, W.B. J. Biol. Chem. 260, 12398–12401 (1985).
Sanchez, E.R. et al. J. Biol. Chem. 262, 6986–6991 (1987).
Pratt, W.B. J. Biol. Chem. 268, 21455–21458 (1993).
Yochem, J. et al. Mol. Gen. Genet. 164, 9–14 (1978).
Liberek, K., Georgopoulos, C. & Zylicz, M. Proc. Natl. Acad. Sci. USA 85, 6632–6636 (1988).
Hwang, D.S., Crooke, E. & Kornberg, A. J. Biol. Chem. 265, 19244–19248 (1990).
Falsone, S.F., Gesslbauer, B., Tirk, F., Piccinini, A.M. & Kungl, A.J. FEBS Lett. 579, 6350–6354 (2005).
Zhao, R. et al. Cell 120, 715–727 (2005).
Qbadou, S. et al. EMBO J. 25, 1836–1847 (2006).
Morita, T., Yamaguchi, H., Amagai, A. & Maeda, Y. Exp. Cell Res. 303, 425–431 (2005).
Smith, D.F., Faber, L.E. & Toft, D.O. J. Biol. Chem. 265, 3996–4003 (1990).
Uehara, Y., Murakami, Y., Sugimoto, Y. & Mizuno, S. Cancer Res. 49, 780–785 (1989).
Prince, T. & Matts, R.L. Biochem. Biophys. Res. Commun. 338, 1447–1454 (2005).
Truman, A.W. et al. Eukaryot. Cell 5, 1914–1924 (2006).
Kamal, A. et al. Nature 425, 407–410 (2003).
Price, J.T. et al. Cancer Res. 65, 4929–4938 (2005).
Banumathy, G., Singh, V., Pavithra, S.R. & Tatu, U. J. Biol. Chem. 278, 18336–18345 (2003).
Chung, E.J., Lee, M.J., Lee, S. & Trepel, J.B. Expert Opin. Drug Metab. Toxicol. 2, 213–230 (2006).
Chiosis, G. Curr. Top. Med. Chem. 6, 1183–1191 (2006).
Gotz, J., Ittner, L.M. & Schonrock, N. Med. J. Aust. 185, 381–384 (2006).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Richter, K., Hendershot, L. & Freeman, B. The cellular world according to Hsp90. Nat Struct Mol Biol 14, 90–94 (2007). https://doi.org/10.1038/nsmb0207-90
Issue Date:
DOI: https://doi.org/10.1038/nsmb0207-90
This article is cited by
-
C0818, a novel curcumin derivative, induces ROS-dependent cytotoxicity in human hepatocellular carcinoma cells in vitro via disruption of Hsp90 function
Acta Pharmacologica Sinica (2022)
-
C1206, a novel curcumin derivative, potently inhibits Hsp90 and human chronic myeloid leukemia cells in vitro
Acta Pharmacologica Sinica (2018)
-
Low concentration of GA activates a preconditioning response in HepG2 cells during oxidative stress—roles of Hsp90 and vimentin
Cell Stress and Chaperones (2009)
-
The activity of hsp90α promoter is regulated by NF-κB transcription factors
Oncogene (2008)