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Paraspeckles: nuclear nests helping to raise mature miRNAs

Nature Structural & Molecular Biology volume 24, pages 783–784 (2017)Cite this article

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The cellular crosstalk between different classes of regulatory noncoding RNAs has reached a new spatial dimension. Jiang et al. reveal an essential role of a nuclear-paraspeckle-organizing long noncoding RNA and its protein partners in regulating the first steps of microRNA biogenesis.

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Figure 1: A nest model of NEAT1-mediated enhancement of miRNA biogenesis.

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  1. the Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

    Jacek Krol

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  1. Jacek Krol
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Correspondence to Jacek Krol.

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Krol, J. Paraspeckles: nuclear nests helping to raise mature miRNAs. Nat Struct Mol Biol 24, 783–784 (2017). https://doi.org/10.1038/nsmb.3479

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