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SMC condensin: promoting cohesion of replicon arms

Nature Structural & Molecular Biology volume 22, pages 653–655 (2015)Cite this article

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Two studies using chromosome conformation capture (3C) analyses in the Gram-positive bacterium Bacillus subtilis have revealed a global pattern of chromosome organization that originates from loading sites of the Smc–ScpAB complex. Loading Smc–ScpAB at a single genomic location is sufficient to promote genome-wide folding of DNA into a well-defined structure.

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Figure 1: Organization of the replicating chromosome in B. subtilis.
Figure 2: Putative scenario for formation of the mitotic chromosome.

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Authors and Affiliations

  1. Frank Bürmann and Stephan Gruber are at the Chromosome Organization and Dynamics Research Group, Max Planck Institute of Biochemistry, Martinsried, Germany.,

    Frank Bürmann & Stephan Gruber

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  1. Frank Bürmann
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  2. Stephan Gruber
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Correspondence to Stephan Gruber.

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The authors declare no competing financial interests.

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Bürmann, F., Gruber, S. SMC condensin: promoting cohesion of replicon arms. Nat Struct Mol Biol 22, 653–655 (2015). https://doi.org/10.1038/nsmb.3082

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