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Synaptic-vesicle fusion: a need for speed

Nature Structural & Molecular Biology volume 22, pages 509–511 (2015)Cite this article

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Two new studies reveal mechanistic insights into how neurons control the assembly of SNARE complexes and the rapid fusion of synaptic vesicles. Structural, biophysical and functional experiments are combined to elucidate the roles of two critical regulators: Munc13 and synaptotagmin.

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Figure 1: Schematic of SNARE-mediated fusion of synaptic vesicles.

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Authors and Affiliations

  1. Mary Munson is at the Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.,

    Mary Munson

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  1. Mary Munson
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Correspondence to Mary Munson.

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The author declares no competing financial interests.

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Munson, M. Synaptic-vesicle fusion: a need for speed. Nat Struct Mol Biol 22, 509–511 (2015). https://doi.org/10.1038/nsmb.3056

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