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Dynactin revealed

Dynactin is an essential cofactor for the microtubule-based motor cytoplasmic dynein. Two recent papers report structures obtained by cryo-EM of dynactin, the dynein–dynactin complex and dynein–dynactin bound to its track, the microtubule.

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Figure 1: Structures of dynactin and dynein–dynactin–BICD2 bound to a microtubule.

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Acknowledgements

I thank Andres Leschziner (Harvard University) for help in generating Figure 1 and for comments on the text.

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Correspondence to Samara L Reck-Peterson.

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Reck-Peterson, S. Dynactin revealed. Nat Struct Mol Biol 22, 359–360 (2015). https://doi.org/10.1038/nsmb.3022

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