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Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein

Nature Structural Biology volume 4, pages 896–899 (1997)Cite this article

The nonstructural protein (NS1 protein) of the influenza A virus binds to several types of RNAs. X-ray crystallographic analysis of the RNA-binding domain reveals a unique topology for the monomer as well as a novel six-helix structure for the dimer.

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Authors and Affiliations

  1. Department of Chemistry, Rutgers University, Wright-Rieman Laboratories, 610 Taylor Road, Piscataway, NJ, 08854-8087, USA

    Jinsong Liu, Patricia A. Lynch, Chen-ya Chien, Gaetano T. Montelione, Robert M. Krug & Helen M. Berman

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  1. Jinsong Liu
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  2. Patricia A. Lynch
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  3. Chen-ya Chien
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  4. Gaetano T. Montelione
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  5. Robert M. Krug
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  6. Helen M. Berman
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Liu, J., Lynch, P., Chien, Cy. et al. Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein. Nat Struct Mol Biol 4, 896–899 (1997). https://doi.org/10.1038/nsb1197-896

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