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Formation of the hinge helix in the lac represser is induced upon binding to the lac operator

Nature Structural Biology volume 3, pages 916–919 (1996)Cite this article

NMR studies of the free and DNA-bound states of the lac represser headpiece show that formation of the hinge helix requires protein–protein interactions and occurs only when the represser binds to the full lac operator.

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Authors and Affiliations

  1. Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH, Utrecht, The Netherlands

    Christian A.E.M. Spronk, Monique Slijper, Robert Kaptein & Rolf Boelens

  2. Gorlaeus Laboratory, University of Leiden, Leiden, The Netherlands

    Jacques H. van Boom

Authors
  1. Christian A.E.M. Spronk
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  2. Monique Slijper
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  3. Jacques H. van Boom
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  4. Robert Kaptein
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  5. Rolf Boelens
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Spronk, C., Slijper, M., van Boom, J. et al. Formation of the hinge helix in the lac represser is induced upon binding to the lac operator. Nat Struct Mol Biol 3, 916–919 (1996). https://doi.org/10.1038/nsb1196-916

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