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Structural genomics in the biotechnology sector

Abstract

Commercial efforts in structural genomics focus on providing to pharmaceutical customers information that relates to the suitability of specific proteins as drug targets and the informed selection and refinement of lead compounds generated by high-throughput screening and rational approaches. These efforts follow a variety of business models and are impacted by activities in the public domain, recent technological advances, and the changing intellectual property landscape.

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Figure 1: Potential impact of structural genomics on drug discovery.

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Dry, S., McCarthy, S. & Harris, T. Structural genomics in the biotechnology sector. Nat Struct Mol Biol 7 (Suppl 11), 946–949 (2000). https://doi.org/10.1038/80718

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