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Blocking HIV entry

Abstract

Targeting the fusogenic machinery of HIV with unnatural ligand libraries.

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Figure 1: Membrane fusion events associated with HIV entry into a target cell.
Figure 2: Stepwise approach to conversion of anti-HIV peptide DP-178 into a small molecule anti-HIV drug.

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Correspondence to Kevan M. Shokat.

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Buzko, O., Shokat, K. Blocking HIV entry. Nat Struct Mol Biol 6, 906–908 (1999). https://doi.org/10.1038/13266

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