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Speeding along the protein folding highway, are we reading the signs correctly?

Nature Structural Biology volume 5, pages 846–848 (1998)Cite this article

Abstract

Detailed studies of submillisecond burst phase signals in non-folding proteins indicate that the observed optical changes may reflect the population of different ensembles of unfolded polypeptides rather than the presence of intermediate species.

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Figure 1: Schematic free energy diagrams illustrating the point that burst phase signals may reflect very different transitions.

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Affiliations

  1. Department of Chemistry and Biochemistry, 0359, University of California San Diego, 9500 Gilman Drive, La Jolla, 92093-0359, California, USA

    Patricia A. Jennings

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  1. Patricia A. Jennings
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Correspondence to Patricia A. Jennings.

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Jennings, P. Speeding along the protein folding highway, are we reading the signs correctly?. Nat Struct Mol Biol 5, 846–848 (1998). https://doi.org/10.1038/2286

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