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The crystal structures of two spermadhesins reveal the CUB domain fold

Spermadhesins, 12,000–14,000 Mr mammalian proteins, include lectins involved in sperm–egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 Å and 1.9 Å resolution respectively.

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Romero, A., Romão, M., Varela, P. et al. The crystal structures of two spermadhesins reveal the CUB domain fold. Nat Struct Mol Biol 4, 783–788 (1997). https://doi.org/10.1038/nsb1097-783

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