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A disulphide-reinforced structural scaffold shared by small proteins with diverse functions

Nature Structural Biology volume 2, pages 835–837 (1995)Cite this article

We describe the T-knot scaffold, a structural feature shared by the EGF-like proteins, ω-toxins and proteinase inhibitors from plants.

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Authors and Affiliations

  1. Laboratory of Mathematical Biology, NCI-FCRDC, Building 469, Room 151, Frederick, Maryland, 21702, USA

    Shuo Liang Lin

  2. Sackler Institute of Molecular Medicine, Tel Aviv University, Tel Aviv, 69978, Israel

    Ruth Nussinov

  3. Laboratory of Mathematical Biology, SAIC/NCI-FCRDC, Building 469, Room 151, Frederick, Maryland, 21702, USA

    Ruth Nussinov

Authors
  1. Shuo Liang Lin
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  2. Ruth Nussinov
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Lin, S., Nussinov, R. A disulphide-reinforced structural scaffold shared by small proteins with diverse functions. Nat Struct Mol Biol 2, 835–837 (1995). https://doi.org/10.1038/nsb1095-835

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