Death-associated protein kinase (DAP-kinase; DAPk) has been implicated in programmed cell death and tumor suppression. The recently solved crystal structure of the catalytic domain of human DAP-kinase reveals interesting 'fingerprint' regions that may be functionally important.
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Acknowledgements
I thank B. Inbal, S. Bialik, G. Shohat and G. Shani for their helpful comments, discussions and advice.
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Kimchi, A. A cell death-promoting kinase. Nat Struct Mol Biol 8, 824–826 (2001). https://doi.org/10.1038/nsb1001-824
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DOI: https://doi.org/10.1038/nsb1001-824
