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The structure of an actin-crosslinking domain from human fimbrin

Nature Structural Biology volume 4, pages 708712 (1997) | Download Citation

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The structure of the N-terminal actin binding domain of human f imbrin offers the first view of an F-actin crosslinking protein and is representative of the conserved actin binding domain found in the largest family of crosslinking proteins. This domain is composed of two calponin homology domains and allows for the mapping of residues implicated in F-actin binding.

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References

  1. 1.

    , , , , and Cell Biol. 111, 1069–1079 (1990).

  2. 2.

    , and Nature Struct. Biology. 4, 175–179 (1997).

  3. 3.

    Seminars in Cell Biol. 5, 165–174 (1994).

  4. 4.

    , and J. Biol. Chem. 266, 12989–12993 (1991).

  5. 5.

    , , and FEBS Letts. 293, 159–162 (1990).

  6. 6.

    , , and FEBS Letts. 298:44–48 (1991).

  7. 7.

    , and FEBS Letts. 344, 255–260 (1994).

  8. 8.

    , and J. Cell Biol. 119, 835–842 (1992).

  9. 9.

    , and J. Cell Biol. in the press (1997).

  10. 10.

    and J. Mol. Biol. 230, 196–205 (1993).

  11. 11.

    , , and J. Cell Biol. 116, 1369–1380 (1992).

  12. 12.

    , and Genetics 140, 91–101 (1995).

  13. 13.

    Appl. Crystallogr. 21, 67–71 (1988).

  14. 14.

    In Proc. of the CCP4 Study Wkd (eds Wolf, W., Evans, P.R., & Leslie, A.G.W.) 80–86. (SERC Laboratory Daresbury, Warrington, UK; 1993).

  15. 15.

    and American Crystallography Association Meeting Abstracts. IB, 73 (1990).

  16. 16.

    X-PLOR (version 3.1): A System for Crystallography and NMR. (Yale Univ. Press, New Haven, Connecticut; 1993).

  17. 17.

    et al. J. Mol. Biol. 112, 535–542 (1977).

  18. 18.

    and J. Mol. Biol. 233, 123–138 (1993).

  19. 19.

    et al. J. Cell Science 108, 63–71 (1995).

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Affiliations

  1. Dept. of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

    • Sharon C. Goldsmith
    • , Alexander A. Fedorov
    •  & Steven C. Almo
  2. Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Nine Cambridge Centre, Cambridge, Massachusetts 02142, USA.

    • Navin Pokala
    • , Wenyan Shen
    •  & Paul Matsudaira
  3. Department of Biology, Massachusetts Institute of Technology, Nine Cambridge Centre, Cambridge, Massachusetts 02142, USA.

    • Paul Matsudaira
  4. Current address: Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA.

    • Navin Pokala
  5. Current address: Amgen Institute, Toronto, Ontario, Canada.

    • Wenyan Shen
  6. almo@aecom.yu.edu

    • Steven C. Almo

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DOI

https://doi.org/10.1038/nsb0997-708

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