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Structural basis of allosteric changes in the GroEL mutant Arg197→Ala

Combined kinetic and cryo-EM analysis of the R197A mutant of GroEL provides insight into the allosteric switching of GroEL, which is at the heart of the chaperonin mechanism.

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White, H., Chen, S., Roseman, A. et al. Structural basis of allosteric changes in the GroEL mutant Arg197→Ala. Nat Struct Mol Biol 4, 690–694 (1997). https://doi.org/10.1038/nsb0997-690

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