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When one and one are not two

Nature Structural Biology volume 2, pages 721–723 (1995)Cite this article

Dimeric proteins can arise from monomers by the simple exchange of secondary structural elements or a wholesale swapping of domains. These results have implications for the construction of novel oligomeric molecules and illuminate how existing structures may have evolved.

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Authors and Affiliations

  1. Department of Chemistry and Biophysics, School of Medicine, University of California San Francisco, California, 94143-0448, USA

    Robert J. Fletterick

  2. Department of Molecular Biology, DNAX Research Institute, 901 California Ave., Palo Alto, California, 94304-1104, USA

    J. Fernando Bazan

Authors
  1. Robert J. Fletterick
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  2. J. Fernando Bazan
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Fletterick, R., Bazan, J. When one and one are not two. Nat Struct Mol Biol 2, 721–723 (1995). https://doi.org/10.1038/nsb0995-721

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