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Actin allostery again?

Nature Structural Biology volume 8, pages 735–736 (2001)Cite this article

The first crystal structure of an actin molecule not associated with another protein has been solved. Remarkably, the most variable part of actin's structure is also the most conserved part of its sequence.

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Figure 1: The actin filament can be built from atomic models of the monomer.
Figure 2: A comparison between subdomain 2 of actin (residues 33–69) as seen in crystals of the G-actin ADP state5 (green) and in crystals of ATP–actin bound to DNase I13 (red).

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  1. the Department of Biochemistry and Molecular Genetics, Box 800733, University of Virginia, Charlottesville, 22908-0733, Virginia, USA

    Edward H. Egelman

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Egelman, E. Actin allostery again?. Nat Struct Mol Biol 8, 735–736 (2001). https://doi.org/10.1038/nsb0901-735

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