Copper is an essential transition metal that plays a fundamental role in the biochemistry of all aerobic organisms. Recent work elucidating the structural mechanisms of copper delivery to superoxide dismutase provides insight into the cell biology of copper metabolism and serves as an example of how to understand the principles governing the incorporation of metals into proteins.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Development of a generic approach to native metalloproteomics: application to the quantitative identification of soluble copper proteins in Escherichia coli
JBIC Journal of Biological Inorganic Chemistry Open Access 11 February 2009
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Linderstrøm-Lang, K.U. Lane medical lectures (Stanford University Press, Stanford; 1952).
Lamb, A.L., Torres, A.S., O'Halloran T.V. & Rosenzweig, A.C. Nature Struct. Biol. 8, 750–754 (2001).
Culotta, V.C. & Gitlin, J.D. in Molecular and metabolic basis of inherited disease (eds Scriver, C.R., Beaudet, A.L., Sly, W. & Valle, D.) 3105–3126 (McGraw-Hill Publishing, New York; 2001).
O'Halloran, T.V. & Culotta, V.C. J. Biol. Chem. 275,25057–25060 (2000).
Rae, T., Schmidt, P., Pufahl, R., Culotta, V.C. & O'Halloran, T.V. Science 284,805–808 (1999).
Outten, C.E & O'Halloran T.V. Science 292, 2488–2492 (2001).
Fridovich, I. Annu. Rev. Biochem. 64, 97–112 (1995).
Wong, P.C. Proc. Natl. Acad. Sci. 97, 2886–2891 (2000).
Lamb, A.L. et al. Nature Struct. Biol. 6, 724–729 (1999).
Lamb, A.L. et al. Biochemistry 39, 1589–1595 (2000).
Casareno, R.L.B., Waggoner, D. & Gitlin, J.D. J. Biol. Chem. 273, 23625–23628 (1998).
Schmidt, P.J. et al. J. Biol. Chem. 274, 23719–23725 (1999).
Schmidt, P.J., Kunst, C. & Culotta, V.C. J. Biol. Chem. 275, 33771–33776 (2000).
Lamb, A.L. et al. Biochemistry 39, 14720–14727 (2000).
Torres, A.S., Petri, V., Rae, T.D. & O'Halloran T.V. J. Biol. Chem. 276, in the press (2001).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bartnikas, T., Gitlin, J. How to make a metalloprotein. Nat Struct Mol Biol 8, 733–734 (2001). https://doi.org/10.1038/nsb0901-733
Issue Date:
DOI: https://doi.org/10.1038/nsb0901-733
This article is cited by
-
Development of a generic approach to native metalloproteomics: application to the quantitative identification of soluble copper proteins in Escherichia coli
JBIC Journal of Biological Inorganic Chemistry (2009)
-
The effects of mitochondrial iron homeostasis on cofactor specificity of superoxide dismutase 2
The EMBO Journal (2006)