Estrogenic 17β-hydroxysteroid dehydrogenase may promote tumour growth in some breast carcinomas. The 2.3 Å structure of the human enzyme complexed with 17β-estradiol gives insight into the specificity of substrate binding.
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Azzi, A., Rehse, P., Zhu, DW. et al. Crystal structure of human estrogenic 17β-hydroxysteroid dehydrogenase complexed with 17β-estradiol. Nat Struct Mol Biol 3, 665–668 (1996). https://doi.org/10.1038/nsb0896-665
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DOI: https://doi.org/10.1038/nsb0896-665
