The chemical properties of cytosine present cells with a serious informational ‘disease’, necessitating enzymes with exquisite specificity for deoxyuridine for its prevention and cure.
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Pearl, L., Savva, R. The problem with pyrimidines. Nat Struct Mol Biol 3, 485–487 (1996). https://doi.org/10.1038/nsb0696-485
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DOI: https://doi.org/10.1038/nsb0696-485