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A Trojan horse with a sweet tooth

The structure determination of an anti-tumour antibody in complex with its Lewis Y carbohydrate antigen is a timely reminder of the historical and immunological importance of antibodies against polysaccharides, as well as their potential medical uses as diagnostics, therapeutics and vaccines.

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Wilson, I., Stanfield, R. A Trojan horse with a sweet tooth. Nat Struct Mol Biol 2, 433–436 (1995). https://doi.org/10.1038/nsb0695-433

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