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The name is bond — H bond


The hydrogen bond plays a critical role in diverse biological phenomena. Although discovered 90 years ago, the precise chemical nature of this unique interaction has remained in dispute. A recent Compton-scattering experiment, however, strongly supports a partially covalent picture of the hydrogen bond.

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Figure 1: Early views of interactions of amide and carbonyl groups in proteins.
Figure 2: Compton scattering from an anisotropic wavefunction.
Figure 3: a, Electron momentum versus anisotropy.
Figure 4: Highly schematic representation of the hydrogen bond.


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The authors would like to thank E. Isaacs for commenting on an early draft of this manuscript, as well as K. Longenecker for assistance.

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Martin, T., Derewenda, Z. The name is bond — H bond. Nat Struct Mol Biol 6, 403–406 (1999).

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