Two recent landmark structures of Src family kinases reveal how a sensitive conformational switch can be built with SH2 and SH3 domains.
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Nguyen, J., Lim, W. How Src exercises self-restraint. Nat Struct Mol Biol 4, 256–260 (1997). https://doi.org/10.1038/nsb0497-256
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DOI: https://doi.org/10.1038/nsb0497-256
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