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Insights into the structure and function of a guide RNP

Nature Structural Biology volume 10, pages 237239 (2003) | Download Citation

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Many different RNA species undergo nucleotide modifications at sites identified by guide small nucleolar ribonucleoprotein (snoRNP) particles. The co-crystal structure of two snoRNP proteins gives valuable clues into the workings of this system.

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References

  1. 1.

    , , , & Cell 85, 1077–1088 (1996).

  2. 2.

    , , & J. Mol. Biol. 260, 178–195 (1996).

  3. 3.

    , & Cell 89, 799–809 (1997).

  4. 4.

    , , & Mol. Cell 2, 629–638 (1998).

  5. 5.

    , , , & Mol. Cell. Biol. 19, 6906–6917 (1999).

  6. 6.

    et al. EMBO J. 20, 2943–2953 (2001).

  7. 7.

    & EMBO J. 20, 541–551 (2001).

  8. 8.

    et al. Proc. Natl. Acad. Sci. USA 97, 14311–14316 (2000).

  9. 9.

    et al. Hum. Mol. Genet. 10, 383–394 (2001).

  10. 10.

    , , , & Hum. Mol. Genet. 11, 1527–1538 (2002).

  11. 11.

    , & Proc. Natl. Acad. Sci. USA 100, 193–198 (2003).

  12. 12.

    , & Science 299, 716–719 (2003).

  13. 13.

    et al. Science 297, 1833–1837 (2002).

  14. 14.

    Science 297, 2215–2218 (2002).

  15. 15.

    et al. Nat. Struct. Biol. 10, 256–263 (2003).

  16. 16.

    & Curr. Opin. Cell Biol. 14, 319–327 (2002).

  17. 17.

    & J. Biol. Chem. 278, 695–698 (2003).

  18. 18.

    , & Methods 23, 276–286 (2001).

  19. 19.

    , , , & Mol. Cell 6, 1331–1342 (2000).

  20. 20.

    , & Mol. Cell. Biol. 22, 8342–8352 (2002).

  21. 21.

    , , & Chem. Biol. 9, 1095–1107 (2002).

  22. 22.

    , , & Proc. Natl. Acad. Sci. USA 99, 5289–5294 (2002).

  23. 23.

    , , , & Cell 72, 443–457 (1993).

  24. 24.

    , , & Gene 302, 129–138 (2003).

  25. 25.

    , , , & EMBO J. 19, 317–323 (2000).

  26. 26.

    et al. Mol. Cell. Biol. 22, 6663–6668 (2002).

  27. 27.

    et al. EMBO J. 21, 3816–3828 (2002).

  28. 28.

    , & EMBO J. 17, 797–807 (1998).

  29. 29.

    & Mol. Cell. Biol. 20, 2650–2659 (2000).

Download references

Author information

Affiliations

  1. Alessandro Fatica is in the Dip. Genetica e Biologia Molecolare, Universita' di Roma “La Sapienza”, P.zzale aldo Moro, 5, 00185 Roma, Italy.

    • Alessandro Fatica
  2. David Tollervey is at the Wellcome Trust Centre for Cell Biology, Swann Building, King's Buildings, Edinburgh EH9 3JR, UK.

    • David Tollervey

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Correspondence to David Tollervey.

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DOI

https://doi.org/10.1038/nsb0403-237

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