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Insights into the structure and function of a guide RNP

Nature Structural & Molecular Biology volume 10, pages 237–239 (2003)Cite this article

Many different RNA species undergo nucleotide modifications at sites identified by guide small nucleolar ribonucleoprotein (snoRNP) particles. The co-crystal structure of two snoRNP proteins gives valuable clues into the workings of this system.

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Figure 1: Schematic of the potential structures of archaeal and eukaryotic box C/D s(no)RNPs and model for methylation site selection.

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Authors and Affiliations

  1. Dip. Genetica e Biologia Molecolare, Universita' di Roma “La Sapienza”, P.zzale aldo Moro, 5, Roma, 00185, Italy

    Alessandro Fatica

  2. the Wellcome Trust Centre for Cell Biology, Swann Building, King's Buildings, Edinburgh, EH9 3JR, UK

    David Tollervey

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  1. Alessandro Fatica
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  2. David Tollervey
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Correspondence to David Tollervey.

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Fatica, A., Tollervey, D. Insights into the structure and function of a guide RNP. Nat Struct Mol Biol 10, 237–239 (2003). https://doi.org/10.1038/nsb0403-237

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