Comparison of two different DMA-binding modes of the NF-κB p50 homodimer

Abstract

Analysis of the NF-κB p50 homodimer bound to different DNA sequences shows that the protein can recognize half-site spacings of either three or four base pairs. The protein can maintain most of its DNA contacts by a relative reorientation of its two domains.

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Müller, C., Rey, F. & Harrison, S. Comparison of two different DMA-binding modes of the NF-κB p50 homodimer. Nat Struct Mol Biol 3, 224–227 (1996). https://doi.org/10.1038/nsb0396-224

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