Hhal methyltransferase, caught in the act of methylating a cytosine on a DNA substrate, reveals how the enzyme overcomes the problem of chemically modifying bases in the relatively inaccessible environment of the DNA duplex.
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Phillips, S. Induced flip. Nat Struct Mol Biol 1, 76–77 (1994). https://doi.org/10.1038/nsb0294-76
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DOI: https://doi.org/10.1038/nsb0294-76