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The RNA binding domain of ribosomal protein L11 is structurally similar to homeodomains

The RNA binding domain of ribosomal protein L11 is strikingly similar to the homeodomain class of eukaryotic DNA binding proteins: it contains three α-helices that superimpose with homeodomain α-helices, and some conserved residues required for rRNA recognition align with homeodomain helix III residues contacting DNA bases.

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Xing, Y., GuhaThakurta, D. & Draper, D. The RNA binding domain of ribosomal protein L11 is structurally similar to homeodomains. Nat Struct Mol Biol 4, 24–27 (1997). https://doi.org/10.1038/nsb0197-24

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